Hi Sean,
Chris has touched on a very important issue.
Chris, wherever you are!
I personally think that the easy access to a myriad of lenses damages us a photographers since we do not get to the numerous rooms of possibilities that one lens for an extended period will provide. I own a lot of lenses. However for the last 2 years 99% of all my DSLR photographs have been with one 50mm lens. It happens to be the 50 1.2 L from Canon, but previously it was the 50mm Pentax Super multicoated Takumar that I used exclusively for 5 years or the 35mm Kodak lens on the Retinette iB which was my lens for another 5 years.
If course, for fashion shoots, runway, weddings, wildlife a special zoom lens came out very often, but this was work.
I feel just using one lens is like having a wife and kids one is devoted too and gets so much back in return. One cannot get that just by being a socialite! Each aperture change and shutter speed provides a different way of writing the image on the film or sensor. With one film camera one digital rangefinder or DSLR (of any make) there is already enough creative possibility to get lost in than you ever good exhaust.
If, OTOH, you are shooting from the sidelines in a hockey game, you'll need a fast DSLR and a fast long lens.
So what is your own intent? I think only you can know that. In Tim Ashley's pictures of that grand salon with peeling walls and the old clock, lens choice with his 1DsII was very important perhaps. I do not know. The end result speaks for itself.
One thing one can do is to try it out. Shoot with just one lens for a month for your self, not for a job. Look at the images. Did it help you express what you needed to or you miss your zoom lens or having ability to switch on the fly.
One thing you are stuck with is that distance to the subject is the one thing that defines perspective. So one works within that limitation.
I wouldn't think about this, just try it out as no one has a ruler in their pocket with your own values and needs engraved on it!
Asher
Now for large landscapes I use an 8x10, but that is another matter.