Just a quick reminder that yew trees are highly poisonous. I suppose that it is the reason why they can be used as chemotherapy, as the effect of the therapy is to kill cancer cells, but it is all in the doses. A bit more and the poison will kill the healthy cells as well.
It’s little more elegant than that.
The drug from the trees increases thr production of micro tubules in the cancer cells but spares normal cells. That's the requirement of most safe and effective anti cancer cells.
In addition, normal cells have ready sleeping non dividing cells in reserve that quickly repopulate any effected tissue, replacing cells to maintain normal tissue function.
As to “dose”, even essentials like water, Na and K, in excess, can kill us.
In chemotherapy, dosage is kept within very accurate safe limits and the expected side effects like nausea are dealt with in advance by medication and extra hydration!
Look at the miraculous effect, a man can have testicular cancer spread with cannon balls of tumor throughout both lungs and Einhorn’s 50 year old regimen of cis_platinum based chemotherapy can cure many if not most of them in thr first round of chemotherapy treatment scheduled!
We live in an era of miracles where friends and family, who would otherwise die, can be routinely cured at the price of a modern SUV!
Asher